In Information Technologies and Communications era, many enterprises search for new ways to improve relationships with customers and suppliers, with other enterprises, following to reduce the business processes risks, optimize the stocks, adopting some essential decisions. Investments in information technologies became priority for enterprises, which are used for systems of e-business management, currently. Using this system must reduce: spore of productivity, reducing production costs, remove negative effects from that enterprise activity, profit spore, advanced protection, safe information content, availability, permanent control, and others. These indicators can be estimated (we have some proposals) to obtain a quantification of the usage efficiency of systems of e-business management. In this paper, it is presented a lot of idea regarding the economic efficiency assessment by using a system of e-business management, the calculation of some indicators, assessment of information systems risks and proposing of some measures to counteract them to assure data security.